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TAILORED DIFFUSE EMITTERS FOR CANCER THERAPY

Existing methods for photodynamic therapy, e.g. for the treatment of tumors and other tissue changes, are currently based on light-scattering fiber tips, which, however, are only partially suitable for spatially selective illumination in more complex structures.

In order to achieve better results for this form of therapy, the Otto Schott Institute of Materials Research (OSI) under the initiative of Prof. Lothar Wondraczek, developed an approach for interstitial illumination based on fiber-integrated light diffusers, were the radiation profile can be adjusted along the fiber.
The experimental part of this task was carried out at our institute under the supervision of Prof. Stefan Nolte, whereby the optical glass fibers were modified by means of ultra-short pulse laser material processing, without mechanical destruction. The aim was to place the induced scattering centers along the fiber in such a way that the waveguide radiates homogeneously over its length.
The theoretical part was developed at OSI, which also carried out the detailed evaluation of the experimental results. The investigations have shown that the radiation profile depends on various scattering mechanisms and the interaction of light modes in the fiber core and cladding.
The results were jointly published at https://doi.org/10.1364/OME.9.002497
- the editor of Optical Material Express awarded the article the so-called "Editor's Pick" to highlight the excellent scientific quality of the work.

glas fiber
Rights: IAP-FSU.

Publication:
Aaron Reupert, Maximilian Heck, Stefan Nolte, Lothar Wondraczek, Side-emission properties of femtosecond laser induced scattering centers in optical fibers, Optical Materials Express, 9(6), pp. 2497-2510 (2019).


News from: 13.05.2019 13:17
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